Polymorphisms of mitochondrial DNA control region are associated to endometriosis
نویسندگان
چکیده
منابع مشابه
Mitochondrial Haplogroups and Control Region Polymorphisms Are Not Associated with Prostate Cancer in Middle European Caucasians
BACKGROUND Besides being responsible for energy production in the cell, mitochondria are central players in apoptosis as well as the main source of harmful reactive oxygen species. Therefore, it can be hypothesised that sequence variation in the mitochondrial genome is a contributing factor to the etiology of diseases related to these different cellular events, including cancer. The aim of the ...
متن کاملInvestigation of Polymorphisms in Non-Coding Region of Human Mitochondrial DNA in 31 Iranian Hypertrophic Cardiomyopathy (HCM) Patients
The D-loop region is a hot spot for mitochondrial DNA (mtDNA) alterations, containing two hypervariable segments, HVS-I and HVS-II. In order to identify polymorphic sites and potential genetic background accounting for Hypertrophic CardioMyopathy (HCM) disease, the complete non-coding region of mtDNA from 31 unrelated HCM patients and 45 normal controls were sequenced. The sequences were aligne...
متن کاملPolymorphism of the Mitochondrial DNA Control Region
Intraspecific and interspecific nucleotide sequence variations of the mtDNA control region (D-loop) were studied with mtDNAs isolated from tissue specimens of more than 1400 sturgeons of nine species: Russian sturgeon Acipenser gueldenstaedtii , Persian sturgeon A. persicus , Siberian sturgeon A. baerii , Amur sturgeon A. schrenkii , Fringebarbel sturgeon A. nudiventris , sterlet A. ruthenus , ...
متن کاملAutomated alignment and nomenclature for consistent treatment of polymorphisms in the human mitochondrial DNA control region.
Naming mtDNA sequences by listing only those sites that differ from a reference sequence is the standard practice for describing the observed variations. Consistency in nomenclature is desirable so that all sequences in a database that are concordant with an evidentiary sequence will be found for estimating the rarity of that profile. The operational alignment and nomenclature rules, i.e., "Wil...
متن کاملPolymorphisms in the Mitochondrial DNA Control Region and Frailty in Older Adults
BACKGROUND Mitochondria contribute to the dynamics of cellular metabolism, the production of reactive oxygen species, and apoptotic pathways. Consequently, mitochondrial function has been hypothesized to influence functional decline and vulnerability to disease in later life. Mitochondrial genetic variation may contribute to altered susceptibility to the frailty syndrome in older adults. METH...
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ژورنال
عنوان ژورنال: Journal of Assisted Reproduction and Genetics
سال: 2017
ISSN: 1058-0468,1573-7330
DOI: 10.1007/s10815-017-1082-4